MeCP2 duplication syndrome is a condition that occurs almost exclusively in males and is characterized by moderate to severe intellectual disability. Most people with this condition also have weak muscle tone in infancy, feeding difficulties, poor or absent speech, seizures that may not improve with treatment, or muscle stiffness (spasticity). Individuals with MECP2 duplication syndrome have delayed development of motor skills such as sitting and walking. Approximately one third of people with this condition cannot walk without assistance. Many individuals with MECP2 duplication syndrome have recurrent respiratory tract infections. These respiratory infections are a major cause of death in affected individuals, with almost half succumbing by age 25.
But it doesn’t have to be this way……
The 401 project represents the donation of $401.00 from the families of 200 children by April 1st 2013. One hundred percent of these funds will go towards a potentially life changing experiment underway at the Baylor College of Medicine headed by Huda Zoghbi. With funding in place, the experiment aims to REVERSE this syndrome in the lab.
In addition to the genetic reversal, a second experiment is ready to begin in parallel. This involves the screening of FDA approved pharmaceutics that hold potential to regulate levels of MeCP2. If such a compound can be found during this screen, the implications for our children and thousands like them would be profound.
To better understand the reversal experiment please visit this site:
http://www.rsrt.org/
The duplication reversal experiment will be very similar.
$401.00 for EVERY CHILD on this site…
$401.00 to give the greatest gift.
All donations to the Rett Syndrome Research Trust are tax deductible.
Paypal:
Please click here to donate the $401.00:
Please click here to donate any amount:
Please click here to donate via the Rett Syndrome Research Trust Mecp2 Duplication Fund Website:
Mecp2Duplication Fund
If you would like more information on the 401 project or how you can participate, please email:
info@401project.com
